The Astros are the AL West champs for the fourth time in five years after beating the Rays 3-2 in Houston.
Carlos Correa's three-run home run in the fourth inning drove in all of Houston's runs.
Lance McCullers won his 13th game, allowing two runs in six innings. Ryan Pressly earned his 26th save with a scoreless ninth.
The Astros will match-up with the Chicago White Sox in the ALDS next week.
Brandon Lowe hit a two-run home run for Tampa Bay. Ryan Yarbrough was tagged with the loss after giving up three runs in four-and-two-thirds innings out of the bullpen. The Rays have already clinched home-field advantage in the American League.