The odds that you'll win the $445 million jackpot in Friday's Mega Millions drawing or the $550 million Powerball jackpot on Saturday are really, really bad. The Mega Millions odds are 1 in 302.6 million. That's more than 2,000 times less likely than being killed by a lightning strike or an earthquake.The odds of winning Powerball are only slightly better -- 1 in 292.2 million.This is the first time ever that both games have offered jackpots of $400 million or more at the same time.